- 직위(직급)
- 부교수
- 전화번호
- 6248
- 연구분야
- 사무실
주요연구분야
- Cell Biology, Molecular pathology, Toxicology
주요 논문 및 저서, 학술발표, 수상등
- 1. Jung KT, Oh SH. The role of autophagy in cadmium-induced acute toxicity in glomerular mesangial cells and tracking polyubiquitination of cytoplasmic p53 as a biomarker. Exp Mol Med. 2022 May;54(5):685-696.
2. Lee HY, Oh SH. Arsenite-induced cytotoxicity is regulated by p38-SQSTM1/p62 and JNK-BNIP3L/Nix signaling in lung cancer cells. Biochem Biophys Res Commun. 2022 Jan 8;587:16-23.
3. So KY, Park BH, Oh SH. Cytoplasmic sirtuin 6 translocation mediated by p62 polyubiquitination plays a critical role in cadmium-induced kidney toxicity. Cell Biol Toxicol. 2021 Apr;37(2):193-207.
4. Lee HY, Oh SH. Autophagy-mediated cytoplasmic accumulation of p53 leads to apoptosis through DRAM-BAX in cadmium-exposed human proximal tubular cells. Biochem Biophys Res Commun. 2021 Jan 1;534:128-133.
5. Jung KT, Oh SH. Poly-ubiquitinated p62/SQSTM1-mediated hemeoxygenase-1 stabilization plays a critical role in cadmium-induced apoptosis of mouse monocyte Raw264.7 cells. Biochem Biophys Res Commun. 2019 Nov 5;519(2):409-414.
6. Jung KT, Oh SH. Polyubiquitination of p62/SQSTM1 is a prerequisite for Fas/CD95 aggregation to promote caspase-dependent apoptosis in cadmium-exposed mouse monocyte RAW264.7 cells. Sci Rep. 2019 Aug 22;9(1):12240.
7. So KY, Lee BH, Oh SH. The critical role of autophagy in cadmium-induced immunosuppression regulated by endoplasmic reticulum stress-mediated calpain activation in RAW264.7 mouse monocytes. Toxicology. 2018 Jan 15;393:15-25.
8. So KY, Kim SH, Jung KT, Lee HY, Oh SH. MAPK/JNK1 activation protects cells against cadmium-induced autophagic cell death via differential regulation of catalase and heme oxygenase-1 in oral cancer cells. Toxicol Appl Pharmacol. 2017 Oct 1;332:81-91.
9. So KY, Oh SH. Cadmium-induced heme-oxygenase-1 expression plays dual roles in autophagy and apoptosis and is regulated by both PKC-δ and PKB/Akt activation in NRK52E kidney cells. Toxicology. 2016 Aug 31;370:49-59
10. So KY, Oh SH. Cadmium-induced hemeoxygenase-1 expression plays dual roles in autophagy and apoptosis and is regulated by both PKC-δ and PKB/Akt activation in NRK52E kidney cells. Toxicology. 2016 Aug 31;370:49-59.
11. Park CH, Lee BH, Ahn SG, Yoon JH, Oh SH. Serine 9 and tyrosine 216 phosphorylation of GSK-3β differentially regulates autophagy in acquired cadmium resistance. Toxicol Sci. 2013 Oct;135(2):380-
12. Yoon JH, Ahn SG, Lee BH, Jung SH, Oh SH. Role of autophagy in chemoresistance: regulation of the ATM-mediated DNA-damage signaling pathway through activation of DNA-PKcs and PARP-1. Biochem Pharmacol. 2012 Mar 15;83(6):747-57.
13. Choi CH, Jung YK, Oh SH. Selective induction of catalase-mediated autophagy by dihydrocapsaicin in lung cell lines. Free Radic Biol Med. 2010 Jul 15;49(2):245-57.
14. Choi CH, Jung YK, Oh SH. Autophagy induction by capsaicin in malignant human breast cells is modulated by p38 and extracellular signal-regulated mitogen-activated protein kinases and retards cell death by suppressing endoplasmic reticulum stress-mediated apoptosis. Mol Pharmacol. 2010 Jul;78(1):114-25.
연구분야에 대한 간략한 설명
- 1. Study of apoptosis and autophagy regulation mechanism.
2. Research on human disease control mechanisms through autophagy and cell death
3. Functional study of selective autophagy in human disease.
4. Signal transduction pathway study for cytotoxicity of heavy metals.
